p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms
نویسندگان
چکیده
منابع مشابه
DNA topoisomerase III alpha regulates p53-mediated tumor suppression.
PURPOSE Human DNA topoisomerase III alpha (hTOP3α) is involved in DNA repair surveillance and cell-cycle checkpoints possibly through formatting complex with tumor suppressors. However, its role in cancer development remained unsolved. EXPERIMENTAL DESIGN Coimmunoprecipitation, sucrose gradient, chromatin immunoprecipitation (ChIP), real time PCR, and immunoblotting analyses were performed to...
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The brochure accompanies the symposium and features the consortium and its members. Support by the European Community is gratefully acknowledged.
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ژورنال
عنوان ژورنال: Cancers
سال: 2019
ISSN: 2072-6694
DOI: 10.3390/cancers11121983